Tim Abram
Experienced medical diagnostics developer, cross-functional team leader, and hands-on bioengineer passionate about technology development for improving human health
(2010-2016)
Dissertation topic: "Development of a 'Cytology-on-Chip' Sensor for Monitoring Potentially Malignant Oral Lesions"
(2008-2009)
Thesis topic: "Electrokinetic sample pre-treatment for electrophoretic separations in blood plasma"
(2004-2008)
Organizations: BMES, University Jazz Ensemble
Involved in the continual evolution of Velox's strategic technical direction; Managed collaboration and partnership projects with universities and top diagnostic companies, consistently hitting milestones ahead of deadlines; Preparing the company for Series A fundraising and planning the commercialization roadmap for the first product; Evaluating and selecting contract design and manufacturing partners; working with regulatory consultants to prepare for 510(k) submission.
As Director of R&D, I was responsible for designing and optimizing microfluidic droplet generator devices, thermocycler control hardware and software, and optical fluorescence detection instrumentation; Oversaw the planning and execution of a multitude of projects related to refining and expanding the capabilities of the Velox core platform technology.
Serving as lead R&D engineer for oral cancer application by participating in internal strategic planning for translation of innovative single-cell analysis technology into commercial clinical analysis system
Designed, built, and tested functional prototypes of a fully-integrated microfluidic device resulting in design requirements documentation for high-volume manufacture
Collaborated with clinical team and spearheaded the analysis and interpretation of data from a 999-patient clinical trial
Co-authored research and business plan for successful SBIR grant submission, earning PI $4M in non-dilutive funding for technology commercialization
Incorporated big data analytics practices and developed infrastructure to translate single-cell measurements into meaningful insights for quantifying oral cancer risk
Developed numeric index algorithm for monitoring oral lesion severity
Contracted by Edwards Lifesciences to develop concepts for flexible annuloplasty rings and deployment strategies to allow for future MIS procedures, resulting in an issued international patent (#WO 2012/027500 A2)
Verified equivalent performance of prototypes to traditional solid-core rings through finite element analysis models simulating physiological loading conditions
Instructor – “BMED 111 – Biomedical Engineering Calculations”
Developed lectures and course structure for core biomedical course with over 100 freshmen students, created and assigned homework assignments and midterm exams, held regular office hours to assist students;
Maintained full teaching course-load while pursuing independent research
Lab Instructor – “BMED 420 – Biomaterials”
Developed lab experiments, advised students on class-based and independent research projects, maintained biomaterial testing equipment, delegated lab assistant responsibilities
Single-cell analysis and patient oral cancer risk prediction from the largest cytology-on-chip trial
Automated cytology as a potential minimally invasive tool to monitor patients with Fanconi Anemia
Improving the level of agreement between independent pathologists
Multisample Bio-nano-chip platform
timabram86@gmail.com
(832) 303-9825